If oxygenation of a cell decreases, the cell's sensitivity to sparsely ionizing radiation will:

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Multiple Choice

If oxygenation of a cell decreases, the cell's sensitivity to sparsely ionizing radiation will:

Explanation:
Oxygen boosts the effectiveness of low-LET (sparsely ionizing) radiation by “fixing” radiation-induced free radicals so they become permanent DNA damage. In well-oxygenated cells, these radicals are stabilized, leading to more cell killing. If oxygen levels drop, fewer radicals are fixed, more damage can be repaired, and the cell becomes less sensitive to the radiation. So when oxygenation decreases, the cell’s sensitivity to sparsely ionizing radiation decreases (it becomes more radioresistant).

Oxygen boosts the effectiveness of low-LET (sparsely ionizing) radiation by “fixing” radiation-induced free radicals so they become permanent DNA damage. In well-oxygenated cells, these radicals are stabilized, leading to more cell killing. If oxygen levels drop, fewer radicals are fixed, more damage can be repaired, and the cell becomes less sensitive to the radiation. So when oxygenation decreases, the cell’s sensitivity to sparsely ionizing radiation decreases (it becomes more radioresistant).

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